[Nausea and dystonia in a woman with psychiatric illness].
| Authors | Orlovska-Waast Sonja, Petersen Iben Rix, Sonne David Peick |
|---|---|
| Journal | Ugeskr Laeger |
| Published | 2026 Mar 02 |
| PMID | 41848246 |
| DOI | 10.61409/V08250624 |
| Source | PubMed |
| Digest | Digest #2 |
Abstract
A woman with complex psychiatric illness and substance use disorder presented with nausea, vomiting, and episodes of oculogyric crisis. A medication review suggested drug-induced acute dystonia, likely triggered by metoclopramide. Other symptoms were possibly related to cumulative anticholinergic effects. Fluoxetine, a potent CYP2D6 inhibitor, may have increased exposure to metoclopramide and promethazine. This case report demonstrates that pharmacological insight and deprescribing can improve s...